Amrita School of Engineering

 

Amrita Schools of Engineering (ASE) »   ASE Coimbatore »   Dept of Electronics Engg »   Faculty »   Dr. P. Gopinath

Dr. Gopinath P.
Assistant Professor
Qualification: Ph. D.
Email: p_gopinath(at)cb.amrita.edu

Research Interest

• Tissue Engineering.
• Biomedical Nanotechnology.
• Biomaterials.
• Drug Designing and Delivery Systems.

Publications

International Journal

• P. Gopinath, S. K. Gogoi, P.Sanpui, A. Paul, A. Chattopadhyay and S. S. Ghosh, "Signaling Gene Cascade in Silver Nanoparticle Induced Apoptosis", Colloids and Surfaces B: Biointerfaces, 77(2):240-5, 2010.
• Roman J., Rangasamy T., Guo J., Sugunan S., Meednu N., Gopinath Packirisamy, Shimoda L., Golding A., Semenza G. and Georas S. N., "T Cell Activation Under Hypoxic Conditions Enhances Interferon-gamma Secretion", American Journal of Respiratory Cell and Molecular Biology, 42, 123-128, 2010.
• P. Gopinath and S. S. Ghosh, "Understanding Apoptotic Signaling Pathways in Cytosine Deaminase-Uracil Phosphoribosyl Transferase Mediated Suicide Gene Therapy in Vitro", Molecular and Cellular Biochemistry, 324, 21-29, 2009.
• P. Gopinath, S. K. Gogoi, A. Chattopadhyay and S. S. Ghosh, "Implications of Silver Nanoparticle Induced Cell Apoptosis for in vitro Gene Therapy", Nanotechnology, 19 (7), 2008.
• P. Gopinath and S. S. Ghosh, "Implication of Functional Activity for Determining Therapeutic Efficacy of Suicide Genes in Vitro", Biotechnology Letters, 30, 1913-1921, 2008.
• P. Gopinath and S. S. Ghosh, "Apoptotic Induction with Bifunctional E. coli Cytosine Deaminase- Uracil Phosphoribosyltransferase Mediated Suicide Gene Therapy Is Synergized By Curcumin Treatment in vitro", Molecular Biotechnology, 39, 39-48, 2008.
• P. Gopinath and S. S. Ghosh, "Monitoring Green Fluorescent Protein for Functional Delivery of E. coli Cytosine Deaminase Suicide Gene and the Effect of Curcumin in vitro", Gene Therapy and Molecular Biology, 11, 219-228, 2007.
• S. K. Gogoi, P. Gopinath, A. Paul, A. Ramesh, S. S. Ghosh, and A. Chattopadhyay, "Green Fluorescent Protein Expressing Escherichia Coli as a Model System for Investigating the Antimicrobial Activities of Silver Nanoparticles", Langmuir, 22, 9322-9328, 2008.
• S. S. Ghosh, P. Gopinath, and A. Ramesh, "Adenoviral Vectors: A Promising Tool for Gene Therapy", Applied Biochemistry and Biotechnology, 133 (1), 9-29, 2006.

International Conference

• Packirisamy G., Bhatt S., Tuder R. M., Prockop D., Mustafa, Mitzner W., Georas S. N, and Rangasamy T., "Investigating The Role of Nrf2 in MSC Survival and Functions", Am. J. Respir. Crit. Care Med., 181: A6603, 2010.


• Packirisamy G., Hai T., Tuder R. M., Bhatt S., Mitzner W., Georas S. N., Rangasamy T., "ATF3 Protects Against Elastase-Induced Pulmonary Emphysema In Mice.", Am. J. Respir. Crit. Care Med., 181: A2908, 2010


• Rangasamy T., Packirisamy G., Tuder R. M., Bhatt S., Mitzner W., Georas S. N., "Disruption of p50 Subunit of NF-κB Enhances Susceptibility To Pulmonary Emphysema In Mice", Am. J. Respir. Crit. Care Med.,2010; 181: A2924.


• Rangasamy T., Bhatt S., Packirisamy G., O'Reilly M., Rhonda S., Witsett J., Mitzner W., Georas S. N., "Role of P21 Cip1 In Immunedysregulation And Allergic Asthma.", Am. J. Respir. Crit. Care Med.,2010; 181: A5604


• S.Bhatt, P.Gopinath, A. Singh, M. McIntash, S. Biswal, S. N. Georas, T.Rangasamy, "Generation of Oxidant-Resistant Nrf2 overexpressing Mesenchymal Stem Cells", Am J Respir Crit Care Med,2009;179: A2019


• T. Rangasamy, S. Bhatt, P. Gopinath, D. J. Prockop, R. M. Tuder, S.N. Georas, "Effects of Cigarette Smoke Condensate on Mouse Mesenchymal Stem Cells", Am J Respir Crit Care Med,2009;179: A4174


• P. Gopinath, S. S. Ghosh, "A comparative Study of 5-Flurocytosine/Cytosine Deaminase and Bifunctional Cytosine Deaminase-Uracil Phosphoribosyl Transferase Suicide Gene Therapy System in Presence of Curcumin", presented in the international conference on new horizons in biotechnology (NHBT 2007), Trivandrum, India. November 2007. Abstract No.MB-075. Page No. 298-299


• P. Gopinath, S. S. Ghosh, "Cytosine Deaminase as a Prodrug/Suicidal Gene Therapy System", presented in the 26th annual convention of Indian association for cancer research and international symposium on translational research in cancer (IACR 2007), Bhubaneswar, India. January 2007. Abstract No. A15. Page No. 95

Book

• Gopinath Packirisamy, "Prodrug Gene Therapy Vectors in Combination Therapies- An update", Lambert Academic Publishing (LAP) ISBN 978-3-8383-4650-2.

Press Releases

• An article entitled Treating Cancer was published in "The Times of India-Education times" dated April 21, 2008, regarding our research work on Gene therapy combined with Nanotechnology (silver nanoparticles)


• An article entitled "Advances in Nanomedicine- Understanding the Intricacies of Nanoparticle Drug Delivery" was published in "Nanowerk" dated August 28, 2008 regarding our research work on Gene therapy combined with Nanotechnology (silver nanoparticles). http://www.nanowerk.com/spotlight/spotid=6959.php